<p>Shiv Nadar University is a comprehensive, multidisciplinary, research-focused, and student-centric University offering a full range of academic programs at the undergraduate, postgraduate and doctoral level. With state-of-the-art infrastructure, the University comprises of academic wings, sophisticated labs, international standard sports facilities, amphitheaters, auditorium, conference rooms and smart classrooms. The University&rsquo;s goal is to become internationally recognized for the quality of its research and creative endeavors and their applicability to improving quality of life, generating new insights and expanding the boundaries of human knowledge creativity. Committed to excellence in teaching, research and service, the University aims to serve the higher education needs of India and the world beyond.</p>

Shiv Nadar University

(SoNS) School of Natural Sciences

31P NMR has been done in the paramagnetic state of SmCoPO. Hisohf, Haxhf are 13.4 and -5.19 kOe/$\mu$B respectively have been estimated which indicates the nature of hybridization between P 2p orbitals with Co 3d orbitals. Anisotropic spin-lattice relaxation rate has been observed. In plane spin-correlations are 2D FM and out of plane spin correlations are AFM type. {\textcopyright} 2012 American Institute of Physics.

Physics

World University root node

AIP Conference Proceedings

Anisotropic spin-fluctuations in SmCoPO: 31P NMR study

Chemical and biological network analysis has recently garnered intense interest from the perspective of drug design and discovery. While graph theoretic concepts have a long history in chemistry - predating quantum mechanics - and graphical measures of chemical structures date back to the 1970s, it is only recently with the advent of public repositories of information and availability of high-throughput assays and computational resources that network analysis of large-scale chemical networks, such as protein-protein interaction networks, has become possible. Drug design and discovery are undergoing a paradigm shift, from the notion of 'one target, one drug' to a much more nuanced view that relies on multiple sources of information: genomic, proteomic, metabolomic and so on. This holistic view of drug design is an incredibly daunting undertaking still very much in its infancy. Here, we focus on current developments in graph- and network-centric approaches in chemical and biological informatics, with particular reference to applications in the fields of SAR modeling and drug design. Key insights from the past suggest a path forward via visualization and fusion of multiple sources of chemical network data. © 2012 Future Science Ltd.

Chemistry

Fulltext

Future Medicinal Chemistry

Graphs and networks in chemical and biological informatics: Past, present and future

A novel solution processable donor-acceptor (D-A) based low band gap polymer semiconductor poly{3,6-difuran-2-yl-2,5-di(2-octyldodecyl)-pyrrolo[3,4- c]pyrrole-1,4-dione-alt-thienylenevinylene} (PDPPF-TVT), was designed and synthesized by a Pd-catalyzed Stille coupling route. An electron deficient furan based diketopyrrolopyrrole (DPP) block and electron rich thienylenevinylene (TVT) donor moiety were attached alternately in the polymer backbone. The polymer exhibited good solubility, film forming ability and thermal stability. The polymer exhibits wide absorption bands from 400 nm to 950 nm (UV-vis-NIR region) with absorption maximum centered at 782 nm in thin film. The optical band gap (Eoptg) calculated from the polymer film absorption onset is around 1.37 eV. The π-energy band level (ionization potential) calculated by photoelectron spectroscopy in air (PESA) for PDPPF-TVT is around 5.22 eV. AFM and TEM analyses of the polymer reveal nodular terrace morphology with optimized crystallinity after 200 °C thermal annealing. This polymer exhibits p-channel charge transport characteristics when used as the active semiconductor in organic thin-film transistor (OTFT) devices. The highest hole mobility of 0.13 cm 2 V -1 s -1 is achieved in bottom gate and top-contact OTFT devices with on/off ratios in the range of 10 6-10 7. This work reveals that the replacement of thiophene by furan in DPP copolymers exhibits such a high mobility, which makes DPP furan a promising block for making a wide range of promising polymer semiconductors for broad applications in organic electronics. © The Royal Society of Chemistry 2012.

Journal of Materials Chemistry

Furan substituted diketopyrrolopyrrole and thienylenevinylene based low band gap copolymer for high mobility organic thin film transistors

The recent up to ~2 fb -1 of data from the ATLAS and CMS experiments at the CERN Large Hadron Collider at 7 TeV put an upper bound on the production cross section of a Higgs-like particle. We translate the results of the H→WW→lνlν and H→γγ as well as the combined analysis by the ATLAS and CMS into an allowed region for the Kaluza-Klein (KK) mass M KK and the Higgs mass M H for all the known Universal Extra Dimension (UED) models in five and six dimensions. Our bound is insensitive to the detailed KK mass splitting and mixing and hence complementary to all other known signatures. © 2011 Elsevier B.V.

Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics

A bound on universal extra dimension models from up to 2 fb -1 of LHC data at 7 TeV

The transcriptome of cultivated chickpea (Cicer arietinum L.), an important crop legume, has recently been sequenced. Here, we report sequencing of the transcriptome of wild chickpea, C. reticulatum (PI489777), the progenitor of cultivated chickpea, by GS-FLX 454 technology. The optimized assembly of C. reticulatum transcriptome generated 37265 transcripts in total with an average length of 946bp. A total of 4072 simple sequence repeats (SSRs) could be identified in these transcript sequences, of which at least 561 SSRs were polymorphic between C. arietinum and C. reticulatum. In addition, a total of 36446 single-nucleotide polymorphisms (SNPs) were identified after optimization of probability score, quality score, read depth and consensus base ratio. Several of these SSRs and SNPs could be associated with tissue-specific and transcription factor encoding transcripts. A high proportion (92-94%) of polymorphic SSRs and SNPs identified between the two chickpea species were validated successfully. Further, the estimation of synonymous substitution rates of orthologous transcript pairs suggested that the speciation event for divergence of C. arietinum and C. reticulatum may have happened approximately 0.53million years ago. The results of our study provide a rich resource for exploiting genetic variations in chickpea for breeding programmes. © 2012 The Authors. Plant Biotechnology Journal © 2012 Society for Experimental Biology, Association of Applied Biologists and Blackwell Publishing Ltd.

Life Sciences

Plant Biotechnology Journal

Transcriptome sequencing of wild chickpea as a rich resource for marker development

The traditional frameworks for fuzzy linear optimization problems are inspired by the max-min model proposed by Zimmermann using the Bellman-Zadeh extension principle. This paper attempts to view fuzzy multiobjective linear programming problem (FMOLPP) from a perspective of preference modeling. The fuzzy constraints are viewed as negative preferences for rejecting what is unacceptable while the objective functions are viewed as positive preferences for depicting satisfaction to what is desired. This bipolar view enable us to handle fuzzy constraints and objectives separately and help to combine them in distinct ways. The optimal solution of FMOLPP is the one which maximizes the disjunctive combination of the weighted positive preferences provided it satisfy the negative preferences combined in conjunctive way. © 2012 Springer-Verlag.

Mathematics

Communications in Computer and Information Science

Fuzzy multiobjective linear programming: A bipolar view

We report hole and electron doping in Y0.38La 0.62(Ba2-xLax)Cu3Oy thin films synthesized by the pulsed laser deposition technique and subsequently annealed in oxygen ambient or in a vacuum. X-ray diffraction studies suggested a single phase in p-type thin films and transport measurements showed a superconductor-to-insulator transition at x = 0.46. Hall measurements indicated electrons were successfully doped when the thin films were annealed in vacuum. The n-type samples demonstrated metallic behaviour within moderate temperature ranges, and a low in-plane resistivity (ρab) and a high carrier density for 0.32 ≤ x ≤ 0.46. The increase in ρab for higher La doping levels, probably caused by charge compensation, is also discussed. The present result could be a significant step in searching for electron-doped superconductivity in the YBa2Cu3Oy system. © 2012 IOP Publishing Ltd.

Superconductor Science and Technology

The influence of la substitution and oxygen reduction in ambipolar La-doped YBa2Cu3Oy thin films

Sixty five patients (20 children and 45 adults of both sexes) having hepatomegaly were subjected to serum copper, hepatic copper and hepatic cuproprotein analysis from October 1982 through September 1983. Higher levels of serum copper were encountered in 17/20 children suffering from Indian Childhood Cirrhosis (ICC), values ranging from 151 ug/dl to 350 ug/dl. Hypercupremia was also detected in reactive hepatitis 5/17, portal cirrhosis 2/9, chronic active liver disease (CALD) 3/4, malignancies in liver 3/5 and in the single case of secondary biliary cirrhosis, serum copper was normal in cases of steatosis of liver, Dubin-Johnson Syndrome and congenital hepatic fibrosis. Hepatic copper was detected only in cases of ICC (17/20). Hepatic cuproproteins were also detected in all these cases as intracytoplasmic dark drown granules. In other chronic liver diseases studied, both hepatic copper and cuproproteins were negative. It is proposed that deranged copper metabolism could have a role in the pathogenesis of ICC.

International Journal of Pharma and Bio Sciences

Serum copper and hepatic copper in chronic liver diseases with particular reference to indian childhood cirrhosis

North American Journal of Medical Sciences

Re: Social determinants and its influence on the prevalence of morbidity among adolescent girls

The synthesis of the peptidoglycan cell wall is carefully regulated in time and space. In nature, this essential process occurs in cells that live in fluctuating environments. Here we show that the spatial distributions of specific cell wall proteins in Caulobacter crescentus are sensitive to small external osmotic upshifts. The penicillin-binding protein PBP2, which is commonly branded as an essential cell elongation-specific transpeptidase, switches its localization from a dispersed, patchy pattern to an accumulation at the FtsZ ring location in response to osmotic upshifts as low as 40 mosmol/kg. This osmolality-dependent relocation to the division apparatus is initiated within less than a minute, while restoration to the patchy localization pattern is dependent on cell growth and takes 1 to 2 generations. Cell wall morphogenetic protein RodA and penicillin-binding protein PBP1a also change their spatial distribution by accumulating at the division site in response to external osmotic upshifts. Consistent with its ecological distribution, C. crescentus displays a narrow range of osmotolerance, with an upper limit of 225 mosmol/kg in minimal medium. Collectively, our findings reveal an unsuspected level of environmental regulation of cell wall protein behavior that is likely linked to an ecological adaptation. © 2012, American Society for Microbiology.