Supercritical fluid extraction (SFE) process is the sustainable green process for the extraction. Mathematical modeling of SFE process is carried out using mass transfer resistances, which vary with the types of solute. In this paper, the effect of matrices such as leaves, flower concrete, flower bud, herb plant, shrub seed and vegetable matter is studied on extraction yield through different models. These models are solved using COMSOL Multiphysics 5.2 solver and results are validated with that of literature. Experimental data of each type of solute matrix are fitted in various models and best suited model is predicted. © 2017 Taylor & Francis.