In recent years, the information systems research community has been experiencing an exciting time discovering and coming to grips with many unexplored or untapped opportunities for research that lie at the intersection of the disciplines of information systems and technology, big data, analytics, and data science. In this article, some of the critical aspects of the big data problem are discussed, and their importance as well as relevance to information systems research is shown. Also proposed are a number of research problems in this area that interested information systems scholars can address to delve more deeply into the field as well as to generate further active interest of the subject within the information systems community. © 2016 Jaideep Ghosh.