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Methods for identification and validation of G-quadruplex sequences in legumes
Singh S., Mathur T., Gupta K.,
Published in Humana Press Inc.
PMID: 31893452
Volume: 2107
Pages: 261 - 268
Among the different secondary structures that DNA can adopt, G-quadruplex is a noncanonical form that has recently started to garner attention about the possible layers of regulation they could introduce in cellular processes. Here, we outline how the presence of G-quadruplexes can be probed in legumes and other plant genomes. This chapter describes various in silico approaches that can be utilized to identify putative G-quadruplex forming sequences (GQSes) and validate their formation through in vitro experimental approaches. © Springer Science+Business Media, LLC, part of Springer Nature 2020.
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Published in Humana Press Inc.
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