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Enantioselective synthesis of spirooxoindoles via chiral auxiliary (bicyclic lactam) controlled SNAr reactions
, V.R. Potti, R. Surakanti, Y.L.N. Murthy, R. Pallepogu
Published in
PMID: 20981367
Volume: 9
Issue: 2
Pages: 358 - 360
A highly efficient enantioselective SNAr reaction of chiral acyl bicyclic lactam with substituted-2,4-dinitrobenzenes was developed, affording products containing quarternary stereogenic centers. They are further utilized towards an enantioselective synthesis of spirooxoindoles. © 2011 The Royal Society of Chemistry.
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