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Cerium Chloride Catalyzed, 2-Iodoxybenzoic Acid Mediated Oxidative Dehydrogenation of Multiple Heterocycles at Room Temperature
Published in Wiley-VCH Verlag
2017
Volume: 2017
   
Issue: 9
Pages: 1277 - 1280
Abstract
Catalytic cerium chloride was found to activate 2-iodoxybenzoic acid (IBX) for the oxidative dehydrogenation of tetrahydroisoquinolines, tetrahydro-β-carbolines, and thiazolidines to their dehydrogenated and aromatic forms at room temperature in moderate to excellent yields. The robustness of the protocol was demonstrated by scaling up the reactions to multigram quantities. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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Published in Wiley-VCH Verlag
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